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Arteether This Medication is very useful in treatment of malaria. These Arteether are well looked after before they get dispatched for sale as these life saving medicines are made to take care of our esteemed clients. Some really important technical specifications for this drug are following.
- α / β arteether is a fast acting blood schizonticidal agent for P. falciparum malaria at the erythrocytic stage.
- α /β arteether is concentrated in parasitized erythrocytes.
- The functional group responsible for antimalarial activity of α / β arteether is endoperoxide bridge.
- Iron from the digested haemoglobin of the parasite's victim reduces this bridge, releasing a highly reactive free radical iron species which causes lysis of the parasitic cell.
- Lysis of parasitic cell membrane occurs. Damage includes swelling and deformity of food vacuoles membrane, nuclear membrane, endoplasmic reticulum and formation of autophagic vacuoles.
- It is also proposed that α / β arteether inhibits the protein synthesis and alters the ribosomal organization and endoplasmic reticulum.
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